6β-Chloro-5α-hydr­oxy-20-oxopregnan-3β-yl acetate

نویسندگان

  • Rui M. A. Pinto
  • Jorge A. R. Salvador
  • José A. Paixão
  • Ana Matos Beja
  • Manuela Ramos Silva
چکیده

The title steroid, C(23)H(35)ClO(4), is a pregnane derivative prepared by ring opening of the corresponding 5α,6α-ep-oxy steroid with BiCl(3). There are two symmetry-independent mol-ecules in the asymmetric unit that show no significant differences concerning bond lengths and angles. The conformation of the six-membered rings in both mol-ecules is close to a chair form, while the five-membered ring adopts an envelope conformation. All rings in both mol-ecules are trans-fused. The mol-ecules are held together by an extensive O-H⋯O hydrogen-bonding network.

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عنوان ژورنال:

دوره 64  شماره 

صفحات  -

تاریخ انتشار 2008